EP 44 · 47:11

When the expected dominant trait disappears

From New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics)

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47:11Weirdly, I get all recessive. >> Mhm. >> Even though the purple is the pigment, >> right? Like, so that should be dominant >> because that's the working pigment according to like what I told you about what is dominant and recessive. It's not just arbitrary. It's just like one is the protein is actually working. The other one the protein is not working. here. If I have a true breeding purple and a true breeding green, I'm actually getting no working pigment. I'm getting all green. It's like the opposite of the F1 generation, right? This isn't even getting to F2. This is like in the F1 generation. It's as if Mendele did purple cross white and got all white. >> That's okay. That's fasc which which would not make sense given that the >> given that it was all purple

47:51>> is all had the dominance across. It should have the dominance in all four of the >> offspring. Yeah. Okay. So again, what the hell? >> What's going on there? >> What's going on there? So, so now next thing to do is now I mean, usually what you do is you take that and then you crossbreed with itself. So you do a self-fertilization, but now things are weird. So now let's let's cross it with a true breeding purple again, right? Because let's say something weird happened and I got like recessive recessive here. Um, and then the purple. Or maybe I got like one bit of purple, but like it's not showing up in the in the F2 generation. I should get some purple.

From the episode
  1. EP 44

    New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics)

    A new mouse genetics paper suggests that non-Mendelian epigenetic inheritance may be more common in mammals than previously thought.

    New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics)

BiologyDNAEpigeneticsGeneticsInheritance