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1:16:03quite simple. It's kind of like Mandelian experiments. Okay. What you do is you take your um your you take your CC019 and your CC037 those lines very well established what the epigenetic markers are there and what the genetics are there. So even though they're not like true breeding in a sense you have a good understanding of like what the genetics are. Now you cross them and then you cross those again right just like in Mendle's experiments. But in this case, what we're looking at is the methylation pattern on the chromatin instead of the actual genetic sequence. Y >> okay. So the genetic sequences could be the same, but depending on whether this chromatin came from the mom, this one
1:16:45came from the dad, all of these things are now going to start changing. >> Okay, this is very very and and it and it makes sense now why it would be changing. One, because we understand the sex chromosome, so you get one from each. two because the methylation is going to change what proteins are actually produced or what's suppressed. And so now with all of that understanding and background and context and the ability to actually >> detect and sequence the methylated C um >> nice >> like that that is they can now do real statistical analysis that's meaningful uh in this because they've done they have the correct they've done the mice work they've done all the other
1:17:26background work anyway. So that I think it's all kind of just >> and one final thing that I want to mention before we get into the results is again about methods because we do want to focus on methods in this. So we've got the >> the you've got the model mouse models of