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1:19:41Okay. So, Mandelian baseline. 93% of the time the epigenetics is doing what Mendle's laws say. Here's how we're going to read these figures. Okay? All of the subsequent figures are going to be the same way. Um so, the pink is coming from the mom. The green is coming from the dad. What we're looking at on the y-axis is the percent methylation, the amount of methyl methylation, meaning how much of the C's have a methyl attached to it. Okay, 100% would mean every single C has a methyl group attached. Zero means none of the C's have a methyl attached,
1:20:22right? And what we're looking at on the X-axis is just along the DNA. >> Okay? So along the DNA, you can see that there's a certain region where the mom has almost no methyl groups attached to the C's and the dad has a bunch. >> Mhm. >> Okay. The solid green lines and the solid purple lines are the parent generation and then there's dotted green lines and dotted purple lines for the kids. The key thing to see here is that the dotted green is on top of the solid green and the dotted purple is on top of the solid purple. Meaning the the the methyl pattern of the kids is the same
1:21:02as the the moms or the dads. Okay. Nothing's changed. Like I got the chromatin, I got the methyl. Nothing changed. Nothing weird happened in between. So this is the mandelian baseline. >> Yes. >> Okay. And they they they actually use two different um tissues from the liver and from the muscle >> to see how like if there's any organ dependent effects that are happening. >> That's actually good. That's nice. >> Yeah. So this is this is this is like normal. >> Okay. This is something that um we thought should happen every single time. >> Yes. >> All right. Now, let's look at our first anomaly. >> And because and what we're saying is 93% of the time, Mandelian genetics holds up. >> Yeah. >> But there is the 7% outlier where it doesn't. And that's what >> And that's the
1:21:43>> that's weird. >> Yeah. >> And that's where the weirdness is. Okay. Now, let's look at non-dominant