EP 44 · 15:26

Mendel’s purple and white flower experiment

From New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics)

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15:27he takes the parent generation. Let's let's let's just talk about the flower color right now. There's seven other traits that he could look at, but they all actually obeyed these rules, but it's nice to talk about flower color cuz looks good on TV. Okay, so I'm going to take a true breeding purple and a true breeding white plant. I'm going to breed those two. the first generation. That's the F1, the first filial generation is is how how he put it. That one has all purple. Immediately you notice something weird. You're not getting a mix. >> Mhm. >> Right. You're not getting um like lighter purple >> like pink. >> It's not a blend. >> It's not a blend. >> It's not a mix of half and half. >> It's not even half and half. It's fully

16:07all purple. >> Okay. First thing that's kind of weird. >> Okay. It's almost as if the the first generation is also true breeding, >> right? So you're like, "Hey, so is the first is the white just like doing nothing, >> right? >> Is everything coming from one? >> Is everything just coming from one? What's going on?" That's when you take do the second cross. So you do a second filial F2 generation where you take two of the first generation ones and you cross them. And now you get something weird. You get the white back, but the ratio of purple to white is always, and I mean always 3 to one >> in his notebooks. >> Okay, >> he's got 29,000 plants that he's doing

16:48this with and it's almost always 3:1. Like statistically, that's the ratio that he's getting. Okay, >> I think I see it. This is very weird. It's very So, and with no context and no foundation. >> Yeah. Now, it's like trivial, >> right? But it's it's why did we we had two different the first generation all only similar to one of the two parents but the second generation that was bred from that F1 generation where everything was the same as one parent is a 3:1 ratio of one parent to another. >> Yeah. >> Almost all of the time. >> Almost all of the time. Okay. So let's try to figure out what how this would happen. Okay.

From the episode
  1. EP 44

    New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics)

    A new mouse genetics paper suggests that non-Mendelian epigenetic inheritance may be more common in mammals than previously thought.

    New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics)

BiologyDNAEpigeneticsGeneticsInheritance