EP 44 · 25:17

From mathematical rules to biological mechanisms

From New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics)

Episode
17/55
Watch New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics)
Transcript

232 words · auto-generated from the episode video

25:18realize so these are the three and they rediscover Mendel's work in 1900 and they're like well somebody beat us to the punch And this this is now colloquially known as the rediscovery of Mendel and it launched modern genetics because now they're like okay so there is some kind of level of understanding that we can figure out right >> now the next >> focus is always how do we go from empirical math rules to some kind of mechanistic understanding right what is actually happening right >> in the organism that is doing this >> right so we we can predict but we don't know how it works >> yeah exactly okay So, first first question, natural question. Where are the alals?

25:58>> Yeah. >> Right. You're saying there's these two types of alals. Well, and it seems like there's like actual stuff, >> right? That's like moving like and like there's like physically two thingies that like get independently that come out and then they recombine and stuff like that. But if if that's the case, there should be something I can find inside organisms that is an alil, right? So Walter Sutton, he's a graduate student at Columbia University at the time and he proposes in 1902 1903 that these men these alals are located on chromosomes. Okay, he was actually working on grasshoppers at the time and

From the episode
  1. EP 44

    New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics)

    A new mouse genetics paper suggests that non-Mendelian epigenetic inheritance may be more common in mammals than previously thought.

    New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics)

BiologyDNAEpigeneticsGeneticsInheritance