Reverse transcriptase allows genetic information to be copied from RNA into DNA. The discussion connects this mechanism to viruses integrating genetic material into a host cell’s DNA.
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34:27>> 1968 to 1970, uh viral integration and reverse transcription. >> Yes, this is veriologists Ronaldo Delbuko, um David Baltimore, and Howard Teman. They unmasked how tumor viruses, which had been discovered earlier by another American earlier on our list, they alter host cell DNA by integrating their own genetic material into the DNA. But how is that possible if some of these viruses are made out of RNA? Well, it turns out there's this thing called reverse transcriptise that upends the central dogma model where DNA only goes to RNA. Turns out reverse transcriptise can take RNA back to DNA. This was at
35:08the Sulkq Institute, MIT, and University of Wisconsin Madison. It earned them the 1975 Nobel Prize in Physiology. >> Another topic we've covered a lot on the