MicroRNA is a post-transcriptional regulatory mechanism: after DNA is transcribed into mRNA, microRNAs help control that mRNA's activity. The transcript notes this system is conserved across many species and that it fine-tunes an estimated 60% of human protein-coding genes, with major implications for developmental genetics, oncology, and pharmacology. The discovery was recognized with the 2024 Nobel Prize in Medicine.
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1:33:10deserves. um he discovered microRNA and it proved they proved that um universally it's conserved all across a bunch of species. This microRNA is a fundamental post transcription mechanism. Meaning, you know, I've got DNA, the DNA gets transcribed into mRNA, but then that mRNA gets regulated by these microRNA mechanisms. Um, it's hugely important for RNA biology and developmental genetics, medical therapeutics. It opened up new dimensions for oncology and pharmarmacology. It revealed that 60% of human protein coding genes are actively fine-tuned by these microRNA. That's not
1:33:51a minority. 60%, right? They won the 2024 Nobel Prize in medicine. >> Phenomenal discovery that one. Uh, we are still in 1993, a banger year where we have the invention of the mosaic web browser where we see our favorite egghehead, Mark Andre, and still with some hair on that big brain of his and is the birth of again how we are reaching you all at least one of the ways we're reaching you all today. >> Yeah. Yeah. If you guys are watching on a web browser, you can thank Mark Andre and Eric Bina. They developed the NCSA Mosaic which is a the first sort of web browser um at the University of Illinois