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Watch America 250: The Breakthroughs That Built American Science — Part 2
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RNA polymerase copies information from DNA into RNA. Structural studies of the enzyme helped reveal how this step in gene expression works at the molecular scale.

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1:54:18>> 2001 structural basis of ukareotic transcription. >> Yeah, this is really the final puzzle in the central dogma. We figured out how DNA replicates itself. We figured out how um DNA goes to protein with that um the dictionary of the codons mapping to the amino acids. Um this is how does DNA go to RNA? It's through RNA polymerase. Roger Kornberg used highresolution 3D images of RNA polymerase at Stanford University and revealed the atomic scale structure of this enzyme and how you get that type of transcription. It earned

1:55:00him the 2006 Nobel Prize in chemistry.

From the episode
  1. EP 47

    America 250: The Breakthroughs That Built American Science — Part 2

    Part two of our America 250 special traces American science from Sputnik to the AI age, covering Apollo, ARPANET, CRISPR, LIGO, mRNA vaccines, JWST, transformers, and the future of science funding.

    America 250: The Breakthroughs That Built American Science — Part 2

History of ScienceAmerica 250