Optogenetics is described only in passing as a revolutionary technique now used across university labs to probe the neural circuits of behaving animals in real time. The transcript does not explain the underlying mechanism, who developed it, or when.
193 words · auto-generated from the episode video
1:59:10>> um from from again parts of life. Um this is a revolutionary technology and it's been used in every single university now to probe neural circuits of behaving animals in real time. >> We had a great episode on a breakthrough paper around optogenetics a few episodes back that it's worth taking a look at. We're staying in 2005. uh nucleioide base modifications of mRNA vaccines. Oo, scary. >> Yeah. Well, Caitlyn Carico and Drew Weissman at the University of Pennsylvania, they discovered that you can replace the urodine with pseudouodine in synthetic mRNA and that prevents inflammatory immune responses in our
1:59:52body. So now effectively, you can create vaccines using mRNA very quickly. You don't need to figure out how to keep a virus alive and then kill it and then all this other kind of stuff. You can just give the genetic instruction for whatever antigen, put that into an mRNA, give put it into the body, the body takes care of the rest. It makes the antigen, it trains the immune response, and then all of a sudden you are immune. This is the backbone of the CO 19