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Watch America 250: The Breakthroughs That Built American Science — Part 2
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Cells use repair mechanisms to protect genetic information against errors and damage. The discussion introduces research into how these pathways safeguard DNA, including against ultraviolet damage.

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1:14:12kids do. 1983 mapping of DNA repair mechanisms. Yes. Um DNA when it gets transcribed, when it gets messed with, there's a lot of errors that happen. And yet the error rate for us even is like 1 in a billion. That seems not a lot, >> right? Given just the amount of jiggling that happens at 300 Kelvin >> at our body temperature. So here Paul Modric at Duke University and Aziz Sanchar at UNCC Chapel Hill >> both from North Carolina. They systematically mapped how cells safeguard genetic integrity against

1:14:53mutations and UV damage. And that won them the 2015 Nobel Prize in Chemistry. >> The only time you will see Duke and UNC collaborating uh in a positive way as as arch nemesises in almost every other

From the episode
  1. EP 47

    America 250: The Breakthroughs That Built American Science — Part 2

    Part two of our America 250 special traces American science from Sputnik to the AI age, covering Apollo, ARPANET, CRISPR, LIGO, mRNA vaccines, JWST, transformers, and the future of science funding.

    America 250: The Breakthroughs That Built American Science — Part 2

History of ScienceAmerica 250