Liver-to-blood-to-brain pathway + “exerkines” framing
Transcript
This chapter, from the episode video's captions · 289 words
1:09:16progressed to be the brain, the mind and the body are connected and we need to figure out a holistic understanding of the entire system. Right? And that's where this research comes in. They've identified a biochemical pathway that links the liver to the blood to the brain and it shows the systemic benefits of exercise and how they are transformed or transferred to the brain without actually having to do exercise. That's the idea. >> Oh my goodness. Okay. >> And it's it's able to it's able to >> trace the entire story from exercise to brain benefits. Okay. The mechanism is from a particular enzyme that I'm only
1:09:57going to say once because these biochemists and organic chemistry people. They love just making the the world's longest word. I think that's what they're going for is like Guinness Book of World Records. Anyways, here we go. Okay guys, it's called glycosal phosidal specific phosphipase D1. We are going to refer to this enzyme throughout our story as GPLD1. So whenever you hear me say that word, that is the particular enzyme that we have discovered in the liver and all of its benefits all the way up to the brain. >> I just want to take a brief note to to
1:10:38to distinguish that although it has all of the same letters with a couple of extras. >> This is not ompic. Is that what you're saying? >> It is not a G, we're not talking about GLP1. This is GPLD1. >> Exactly. >> So those are different things. >> Those are very different things. GPLD1, this is not ompic. And what it does is act on blood vessels surrounding the brain to repair age related damage.
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A candidate “dark galaxy”, plus the exercise may protect against Alzheimer’s.