EP 66 · 22:19

Through the skull, and controlling the bubbles

From Destroying Tumors With Sound: Histotripsy with Dr. Zhen Xu

Episode
10/21
Watch Destroying Tumors With Sound: Histotripsy with Dr. Zhen Xu
Transcript

205 words · auto-generated from the episode video

22:21Actually, we covered the transcranial paper in our rundown episode. Yeah, we started with this human skull that they were shooting stuff through to make sure that it would go through a human skull as well, which I thought was pretty incredible. So I wanted to get back to, you know, people said that it would be okay. So now you've done cavitation. Let's say, let's say you've performed controlled cavitation using ultrasounds. Fine. How do you control it? That's the next big thing. It's impossible to control.

23:01And so I have, I wanted to talk to you about two figures from one of your papers that I, as a physicist, I really liked, especially, so this first one is about the nonlinear nature of cavitation probability with respect to pressure. It's kind of like a switch that allows you to control the location on top of the pressure wave itself. And like you're kind of beating the diffraction limit in some sense, which I thought was kind of cool. Yeah, so what happens is that we're all breathing air, like I mentioned. So we add nanometer gas pockets in tissue filtered by the lung and

23:46it's super stabilized with this really high surface tension.

From the episode
  1. EP 66

    Destroying Tumors With Sound: Histotripsy with Dr. Zhen Xu

    Dr. Zhen Xu explains how an unexpected ultrasound result became histotripsy, from bubble physics to liver-tumor treatment and the questions still ahead.

    Destroying Tumors With Sound: Histotripsy with Dr. Zhen Xu

Cancer BioengineeringHistotripsyCancer Research