Topic
Histotripsy
The episodes where the show explains Histotripsy from the ground up.
Episodes2
- EP 66
Destroying Tumors With Sound: Histotripsy with Dr. Zhen Xu
Dr. Zhen Xu explains how an unexpected ultrasound result became histotripsy, from bubble physics to liver-tumor treatment and the questions still ahead.

- EP 59
Golden Goose Awards 2026: The Science Behind the Winners (Part 1)
Explore the science behind the 2026 Golden Goose Awards, from ultrasound that destroys tumors to NASA’s night lights and the deep physics of everyday life.

Chapters from these episodes33
- EP 66 · 0:50A PhD student and a heart problem
- EP 66 · 3:42Heat vs. sound: how histotripsy works
- EP 66 · 7:06Gas pockets, and why not the lungs
- EP 66 · 9:38"Don't read any papers": Yellow Pages and pig hearts
- EP 66 · 12:29Too loud: rethinking the ultrasound pulse
- EP 66 · 14:56"Almost like smoke": the 2002 discovery
- EP 66 · 18:14Building the equipment, and the Edison system
- EP 66 · 23:50The physics: pressure waves, bubbles and cells
- EP 66 · 28:47Ten years to understand it
- EP 66 · 35:58The surprise: an immune response
- EP 66 · 38:16Why liver cancer, and 9 of 11 rats
- EP 66 · 52:27Recovery and the 20-mile-run anecdote
Show 21 more chapters
- EP 66 · 56:24The future: worldwide, kidney, pancreas and brain
- EP 66 · 1:01:33The Golden Goose Award and federal funding
- EP 59 · 2:42Zhen Xu: From a noise complaint to histotripsy
- EP 59 · 5:57The early ultrasound experiments
- EP 59 · 13:42Controlling cavitation with microtripsy
- EP 59 · 20:29Tumor destruction and the immune response
- EP 59 · 28:33Histotripsy through the skull
- EP 59 · 37:23The HOPE4LIVER clinical trial
- EP 59 · 49:20NASA Black Marble: Holiday lights from space
- EP 59 · 55:29Turning night lights into reliable data
- EP 59 · 1:01:36Hurricane Maria and unequal recovery
- EP 59 · 1:08:12COVID-19 and changing nighttime activity
- EP 59 · 1:10:16Mapping access to electricity
- EP 59 · 1:15:20Where Earth is brightening and dimming
- EP 59 · 1:32:57Sidney Nagel and the physics of everyday life
- EP 59 · 1:37:07The science of a falling drop
- EP 59 · 1:46:02Why coffee leaves a ring
- EP 59 · 1:51:04Jamming: When grains become rigid
- EP 59 · 1:53:35A robotic gripper filled with grains
- EP 59 · 1:55:39Why air pressure changes a splash
- EP 59 · 1:58:55Materials that can be trained and retrained