The discovery that became histotripsy

0:00In front of me, I saw there was like almost like a smoke coming out of the pig heart tissue, but it can't be because it's in a water tank. And within a minute, I saw a hole through that pig heart tissue, and I thought I was dreaming. The 11 rats treated, nine of them, not only the tumor didn't spread, the remaining tumor were just gone. We're looking for it everywhere, we couldn't find them. So this crazy patient went out and ran 20 miles within the first week of her tumor treatment. [From First Principles trailer]