EP 56 · 46:40

Evolutionary medicine

From The Yak Mutation That Could Help Repair the Brain

Episode
9/26
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Evolutionary medicine is described as a growing interdisciplinary field that applies evolutionary biology to understanding, preventing, and treating human disease. The reasoning offered is that life has had billions of years to solve survival problems across every environmental niche, with mutations and selective pressure optimizing molecular mechanisms along the way, so medicine can look to those solutions rather than starting from scratch.

Transcript

147 words · auto-generated from the episode video

46:42medicine is a rapidly growing interdisciplinary field. Here's the idea. You basically apply the principles of evolutionary biology to understand, prevent, and treat human diseases because biology has had about 4 billion years to solve random problems. Okay? That have come up in every single niche that life can possibly live in. Right? Life has found a way to live everywhere somehow and to do that it has mutated its genome. It has figured out novel mechanisms by which to solve problems. The environment applies these selective pressures and there's some way in which

47:24in order to si in order to survive a species will optimize some molecular mechanism. >> We're using nature to cheat on the test because nature's been doing the test for way longer than we have. >> Yes. Yeah. Yeah. And in some sense it would be foolish not to >> not to.

From the episode
  1. EP 56

    The Yak Mutation That Could Help Repair the Brain

    A high-altitude genetic adaptation led researchers to a new neuron-to-glia signaling pathway that promotes myelin repair in preclinical models.

    The Yak Mutation That Could Help Repair the Brain

Evolutionary BiologyNeurobiologyPharmacologyRegenerative Medicine