Drug screening: 97% fail (good sign for model fidelity)
Transcript
This chapter, from the episode video's captions · 249 words
2:00:32that we are actually in a new 2.0 foundation for lab testing. >> For lab testing. >> Yeah. >> For lab testing. >> Exactly. And out of the 107, three actually did pretty good. >> Okay. >> Ryuzole, um, Meantene, and Barisicinib, I think that's how you pronounce it. Okay. So let's get into let's get into what these what each of these things are. Um >> rizole is actually something that >> people are already testing nowadays. It was dose dependent. There was significant rescue of this um lethal day 50% metric that I was telling you about. And [snorts] if we look at the physical
2:01:14effect on these neurons there was restored electrical coherence. So on the top row you see just um control on the bottom row they're treated with rizole the neur the neurons are healthier >> right they just look better y >> and it inverted the disease vector so there was a negative correlation >> with like the effect and like how how much time >> the the neurons actually stayed alive. So, it was all a good thing, right? >> The other two, >> they did not confer statistically significant population level benefit. >> So, you think, okay, maybe they're a dud, right? Not so fast. Okay, >> what if we combine >> the drugs, the three drugs that we had a
2:01:56positive effect on, what if we combine them? Is it a synergistic multiplication effect? Right? And that is what they
From Dream Engineering, the Proton Radius Puzzle, and an ALS Breakthrough
Dream engineering, the proton radius puzzle, and a real predictive ALS model.