Deep brain stimulation and the mesocircuit hypothesis

13:10solving." All of that starts forming around this like nucleus. And then the prefrontal cortex being the most advanced. >> That's the one that's like, yeah. >> Right right in the front at the front which sounds You know? It's it's very cool to think about it that way. Just like in terms of stages of development over the millions of years of evolution. Okay, so now we know that it's like kind of the brainstem, but we still don't have really an idea of like Okay, this thing connects to this, this thing connects to this, so this is powering that, that, that, that, and so on and so forth. Um, 2007, there's a pivotal moment in consciousness research because Nicholas Schiff and his colleagues published this paper in nature and it showed that continuous deep brain stimulation. This is the idea

13:52of you we take an electrode and we pulse it with electricity. That is going to excite the neurons near that electrode. It's just you're pumping electricity deep into the brain. That's why it's deep brain stimulation. And deep brain stimulation of the central thalamus helped a minimally conscious patient regain the ability to communicate and feed himself. Okay? This was a very big deal because this was an ability that he had lost about 6 years earlier after a traumatic brain injury. It's a preliminary result, single patient, notoriously inhuman consciousness