Molecular Biology

Molecular Structure of Nucleic Acids: Molecular Structure of Deoxypentose Nucleic Acids

This historic 1953 Nature paper by Wilkins, Stokes, and Wilson provided crucial X-ray crystallographic evidence supporting the double helix structure of DNA.

In plain English

Imagine DNA as a twisted ladder, where the sides are made of sugar and phosphate molecules, and the rungs are pairs of nitrogenous bases. This paper helps us understand how these components fit together to form the structure of DNA, which is like the instruction manual for building and maintaining living organisms.

On the show1
  1. EP 19

    The Race to the Double Helix — Watson, Crick, Franklin & the Real Story of DNA

    A single-story deep dive on DNA's discovery and its moral baggage.

    The Race to the Double Helix — Watson, Crick, Franklin & the Real Story of DNA