A protein switch can be compared with a transistor because its output depends on an input. The analogy motivates optovolution: selecting proteins that respond to changing signals rather than simply maximizing activity in one state. These are molecular control functions, not miniature versions of a general-purpose electronic computer.
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8:10>> It's effectively acting like a molecular transistor in some sense, right? There's an onoff switch. There's a zero and one. And we don't want a protein that's either always zero or always one. >> We don't want to be always asleep or always awake. >> Yeah. Yeah. We want we want things that actually wake up and do things based on their particular environment. And that's where this paper comes in. Okay. This paper is called light directed evolution of dynamic multi-state and computational protein functionalities. That's what they're doing. They're using light to do this directed evolution and from that they can actually figure out ways to create dynamic proteins. That's the optoe evolution um solution that we have. And
8:53so before we get into the mechanics of all that, >> yes, >> let's do a little bit of housekeeping. >> Yes. So, I think I want people to understand how incredible it is to be able to have the opportunity to have this show and to talk to you about Breaking Science news stories every week. As some of you who
Molecular BiologyProtein EngineeringSynthetic BiologyBioengineering