Topic
Microglia
Episodes and research papers from From First Principles that help explain Microglia from the ground up.
Research
Papers and studies featured by the show.
Nature·
Lymphoid gene expression supports neuroprotective microglia function
Brain immune cells called microglia can either protect against or worsen Alzheimer's disease, and scientists found that a specific protein called CD28 helps these cells stay in "protective mode" by reducing harmful brain inflammation. This discovery could lead to new treatments that boost the brain's natural defenses against Alzheimer's.