Research paper

Subretinal Photovoltaic Implant to Restore Vision in Geographic Atrophy Due to AMD

Geographic atrophy is an advanced form of age-related macular degeneration that leads to irreversible central vision loss, affecting millions of people worldwide with no current treatment options. This photovoltaic implant technology represents a potential breakthrough that could restore functional vision to people who have lost their central sight, dramatically improving their quality of life and independence in daily activities like reading, recognizing faces, and navigating their environment.

In plain English

A new eye implant called the PRIMA system helped restore central vision in people with geographic atrophy, a severe form of age-related macular degeneration that causes blindness. After 12 months, patients showed significant improvement in their ability to see, offering hope for treating a condition that currently has no cure.

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Key findings4
  1. 01

    The PRIMA system is a subretinal photovoltaic implant that can restore central vision in patients with geographic atrophy

  2. 02

    38 participants with geographic atrophy due to AMD were included in the clinical trial

  3. 03

    Visual acuity improved significantly from baseline measurements to 12 months after implantation

  4. 04

    The study was funded by Science Corporation and registered as a clinical trial (NCT04676854)

Abstract

In this study involving 38 participants with geographic atrophy due to AMD, the PRIMA system restored central vision and led to a significant improvement in visual acuity from baseline to month 12. (Funded by Science Corporation and the Moorfields National Institute for Health and Care Research Biomedical Research Centre; PRIMAvera ClinicalTrials.gov number, NCT04676854.).