Reward circuitry

Cholinergic interneurons control local circuit activity and cocaine conditioning

In plain English

Manipulating cholinergic interneurons established their influence on local nucleus accumbens activity and cocaine conditioning in animal experiments.

On the show1
  1. EP 61

    Nobel Prize in Medicine 2026 Explained: Optogenetics

    How did proteins from algae give scientists control over brain cells? We explain the 2026 Medicine Nobel, optogenetics, memory experiments and early medical applications.

    Nobel Prize in Medicine 2026 Explained: Optogenetics
Authors9

Ilana B Witten, Shih-Chun Lin, Matthew Brodsky, Rohit Prakash, Ilka Diester, Polina Anikeeva, Viviana Gradinaru, Charu Ramakrishnan, Karl Deisseroth