Krishna’s Top 5 — programmable synthetic proteins (Yale)

59:32exclusive but those were good. And so okay, now let me start with mine. My first one is the programmable synthetic proteins. This was episode three. This one just like blew my mind. It was out of Yale University. Um, effectively, yeah, boo. But also, wow. >> Wow. >> Because [laughter] >> they they effectively like, you know, we're used to 20 building blocks when we create proteins and they're like, "What if we could have 60?" >> Yes. >> You know, because the it takes three codons, three, sorry, it takes three nucleotides to create a codon. So three ATGC's that's four choices in three bins. So four to the three is 64. You need a few

1:00:13of them to tell your protein machinery to start creating a protein and stop creating a protein. But the question is all of that others. >> Yes, >> you know all of those the rest of the 60 are getting mapped on to 20. What if I could map them on to 60? And this was the first step in that, right? They they they made a fully