From First Principles — a science podcast also known as the FFP Pod

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Black Hole Movies, Digital Heart Twins, and World Cup Tech

From an Earth-sized telescope imaging a changing black hole to digital heart surgery and World Cup sensor controversies, this rundown explores the science behind some of today’s most fascinating stories.

From First Principles

Breaking down science news so it makes sense to curious people everywhere.

A weekly video podcast. Watch, listen, or both.

As Seen On

The Dave Chang Show

Netflix · March 12, 2026

Dave Chang introduces From First Principles to his audience — in his own words.

Clip from The Dave Chang Show, Netflix. Used with reference to our guest appearance.

Featured Coverage

Nobel Prize Deep Dives

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Our breakdown of every 2025 Nobel Prize.

Physics

2025 Nobel Prize in Physics

Macroscopic quantum tunneling and energy quantization — the experiments that proved quantum mechanics works at a scale you can hold in your hand.

Recent Episodes

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America 250: The Breakthroughs That Built American Science — Part 2
EP 47

America 250: The Breakthroughs That Built American Science — Part 2

Part two of our America 250 special traces American science from Sputnik to the AI age, covering Apollo, ARPANET, CRISPR, LIGO, mRNA vaccines, JWST, transformers, and the future of science funding.

America 250: The Breakthroughs That Built American Science — Part 1
EP 46

America 250: The Breakthroughs That Built American Science — Part 1

Part one of our America 250 special traces the inventions, institutions, and scientific breakthroughs — from Franklin to Sputnik — that helped build the United States into a global scientific power.

The Physics of the World Cup: VAR, Smart Balls, and Soccer Aerodynamics
EP 45

The Physics of the World Cup: VAR, Smart Balls, and Soccer Aerodynamics

A World Cup special on the science behind the beautiful game, from VAR and smart-ball sensors to soccer ball aerodynamics, pitch engineering, and match momentum analytics.

New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics)
EP 44

New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics)

A new mouse genetics paper suggests that non-Mendelian epigenetic inheritance may be more common in mammals than previously thought.

Dr. Michael Blanton on Open Data, Galaxy Surveys, and the Future of Astronomy
EP 43

Dr. Michael Blanton on Open Data, Galaxy Surveys, and the Future of Astronomy

Dr. Michael Blanton joins us to talk SDSS, open data, Rubin, Carnegie, and the mystery of why the universe’s biggest galaxies stop forming stars.

How Scientists Actually Study Dark Matter
EP 42

How Scientists Actually Study Dark Matter

A first principles interview with astrophysicist Dan Gilman on what dark matter is, why strong gravitational lensing matters, and how the next generation of surveys could reveal the universe’s hidden structure.

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Science News

M87's black hole flipped its magnetic field

Imagine a bar magnet with a north and south pole. Now imagine that magnet suddenly flipping so north becomes south and vice versa. That's essentially what happened with the magnetic field around the giant black hole at the center of galaxy M87 — except this black hole is 6.5 billion times heavier than our Sun. Scientists noticed this flip by watching the powerful beam of energy, called a jet, that shoots out from the black hole. The direction and behavior of that beam changed in a way that revealed the magnetic field had reversed. It's a big deal because those magnetic fields are thought to act like the engine that powers and steers these cosmic jets, and we've rarely caught one flipping in action.

Scientific American·

The 2026 World Cup's grass is an engineering problem

Imagine you're trying to play soccer in 16 different places across the United States, Canada, and Mexico — some in freezing cold, some blazing hot, some in stadiums with roofs that block sunlight. Half of those stadiums normally use fake grass. Now FIFA, the organization that runs the World Cup, wants every single pitch to feel and play exactly the same way, like a video game where every level has identical physics. To do that, they hired grass scientists — yes, that's a real job — who figured out how to grow special grass on thin mats with plastic underneath so it can be transported like a carpet, stitched with synthetic fibers so it doesn't rip when players sprint and tackle, and tested by literally shooting balls at it with a cannon to make sure it bounces right. Different grass species are used depending on whether a stadium is hot, cool, or dark. It's basically a giant, living, high-tech floor installation that has to survive the world's best athletes running on it.

Nature Genetics·

Non-Mendelian inheritance of DNA methylation patterns in mice

Imagine your DNA is like a huge book of instructions. Mendel's laws are the normal rules for how chapters of that book get passed from parents to children. But there's also a layer of sticky notes on top of the book—called epigenetic marks—that tell cells which chapters to read and which to ignore. This study found that most of the time (about 93%), these sticky notes follow the normal inheritance rules. But about 7% of the time, they do something unexpected: new patterns appear that neither parent had, or a mark from one parent somehow silences the same mark from the other parent (called paramutation), or males and females end up with completely different sticky notes even when they inherit the same DNA. Scientists discovered this by using a new ultra-precise DNA reading technology in mice, and it opens the door to understanding hidden layers of how traits—and possibly diseases—are passed down through generations.

New England Journal of Medicine·

Digital twin–guided ablation for ventricular tachycardia

Imagine your heart is a city, and ventricular tachycardia is like a traffic jam caused by a broken road — electrical signals get stuck going in circles instead of flowing properly, causing the heart to beat dangerously fast. Doctors can fix this by burning away the broken road using a procedure called ablation. The problem is, finding the exact broken road inside a beating heart is like navigating a city you've never visited before, while driving, in the dark. What these researchers did is take detailed MRI pictures of each patient's heart, build a 3D computer copy — a 'digital twin' — and then simulate where the electrical problem was happening inside that virtual heart. They tested their fix on the computer model first, figured out exactly where to go, and THEN performed the real procedure. What used to take three hours of exploratory surgery was done in about 30 minutes, because the doctors already had a GPS map before they started.

Nature Neuroscience·

Adversarial AI reveals mechanisms and treatments for disorders of consciousness

Imagine your brain is like a city with millions of roads and traffic systems. When you're awake and conscious, traffic flows in complex, coordinated patterns. In a coma, something has gone wrong — but we've never had a great way to figure out exactly which roads are broken or how to fix them. This study built a very smart AI that learned to tell the difference between 'awake brain' and 'coma brain' by studying hundreds of thousands of brainwave recordings. Then, like a detective, the AI was pitted against a simulated model of the brain to figure out: what changes in the brain's wiring would explain the difference? The AI figured out — on its own, without being told — that two key things go wrong in a coma: a specific circuit deep in the brain (called the basal ganglia indirect pathway) gets disrupted, and the brain's 'braking system' (inhibitory neurons) starts working too hard in the wrong places. The researchers then checked these predictions against real patient data, and both checked out. The AI also suggested that zapping a specific deep brain region with high-frequency electrical pulses might help wake people up — and early evidence from human patients supports this idea.

Applied Sciences·

Trionda: Enhanced Surface Roughness Relative to Previous FIFA World Cup Match Balls

Imagine throwing a ball through air. The air pushes back on the ball, slowing it down—that's called drag. But something interesting happens: at a certain speed, the air flowing around the ball switches from a smooth, lazy flow to a chaotic, turbulent flow, and paradoxically the ball actually experiences LESS drag in that turbulent zone. Think of it like a golf ball—those dimples are there precisely to trigger this turbulence early and make the ball fly farther. The speed at which this switch happens is called the 'critical speed' or 'drag crisis.' Scientists put the Trionda ball in a wind tunnel—basically a giant fan tube—and measured exactly how much air resistance it faces at different speeds. They found that Trionda's surface is effectively rougher than most previous World Cup balls, meaning it hits that drag crisis switch at a lower speed (11.9 meters per second, roughly 27 mph). In plain terms, Trionda behaves more predictably in flight than some past balls, but very long, powerful kicks may travel slightly shorter distances than they would have with previous balls.